Regulation of calreticulin–major histocompatibility complex (MHC) class I interactions by ATP
نویسندگان
چکیده
منابع مشابه
Regulation of calreticulin-major histocompatibility complex (MHC) class I interactions by ATP.
The MHC class I peptide loading complex (PLC) facilitates the assembly of MHC class I molecules with peptides, but factors that regulate the stability and dynamics of the assembly complex are largely uncharacterized. Based on initial findings that ATP, in addition to MHC class I-specific peptide, is able to induce MHC class I dissociation from the PLC, we investigated the interaction of ATP wit...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2015
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1510132112